2011 VU University Medical Center Offers Doctorate Position Physics of Spine Development, Netherlands
PhD Position in the field of Physics of Spine Development at VU University Medical Center in Netherlands-2011
Study Subject(s):Physics of Spine Development
Course Level:PhD
Scholarship Provider: VU University Medical Center
Course Level:PhD
Scholarship Provider: VU University Medical Center
Scholarship can be taken at: Netherlands
Eligibility:The candidate we are looking for should be recently graduated from a MSc program in physics, biochemistry, medical physics, or strongly related field. Other requirements are: Knowledge and experience in soft matter physics or materials science; Additional experience with cells or biomolecules is a plus; Strong affinity for multidisciplinary research; Capacity to write and communicate fluently in English.
Scholarship Open for International Students: No
Scholarship Description: The spine is a highly complex and remarkable structure: it consists of a stack of bony vertebrae separated by cartilaginous intervertebral discs which act as elastic hinges. It is an open question how such complex functional structures form during embryonic development. It appears that physical processes play a pivotal role, since the architectures of both the vertebral bone and the intervertebral disc seem optimally structured to deal with specific mechanical loads.Your position is part of a recently granted (VICI-award) multi-disciplinary research program on the self-organisation of structured connective tissues. The leading hypothesis is that mechanical cues steer the activity of cells as well as the assembly and alignment of extracellular matrix molecules. The aims of this PhD project are to measure the physical cell-cell and cell-matrix interactions by optical tweazers; to elucidate the extra-cellular process of matrix self-assembly by microscopy; and to measure the mechanical properties of cells and extracellular matrix components by microrheology. Other PhD positions within this program will address the developmental biology of the spine and computational modeling of self-assembly in connective tissues.
Scholarship Description: The spine is a highly complex and remarkable structure: it consists of a stack of bony vertebrae separated by cartilaginous intervertebral discs which act as elastic hinges. It is an open question how such complex functional structures form during embryonic development. It appears that physical processes play a pivotal role, since the architectures of both the vertebral bone and the intervertebral disc seem optimally structured to deal with specific mechanical loads.Your position is part of a recently granted (VICI-award) multi-disciplinary research program on the self-organisation of structured connective tissues. The leading hypothesis is that mechanical cues steer the activity of cells as well as the assembly and alignment of extracellular matrix molecules. The aims of this PhD project are to measure the physical cell-cell and cell-matrix interactions by optical tweazers; to elucidate the extra-cellular process of matrix self-assembly by microscopy; and to measure the mechanical properties of cells and extracellular matrix components by microrheology. Other PhD positions within this program will address the developmental biology of the spine and computational modeling of self-assembly in connective tissues.
How to Apply: Online
Scholarship Application Deadline: Until 31 may 2011
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